Skeletal Muscle Relaxants

Pancuronium

0.04–0.1 mg/kg i.v.;
PAVULON, PANURON, NEOCURON 2 mg/ml in 2 ml amp.


Doxacurium

0.03–0.08 mg/kg i.v.


Pipecuronium

0.05–0.08 mg/kg i.v.;

ARDUAN 4 mg/2 ml inj.


Vecuronium

0.08–0.1 mg/kg i.v.;

NORCURON, NEOVEC 4 mg amp. and 10 mg vial; dissolve in 1–2.5 ml solvent supplied.


Atracurium

0.3–0.6 mg/kg i.v.;

TACRIUM 10 mg/ml in 2 ml vial.


Cisatracurium

0.15–0.2 mg/kg i.v.


Rocuronium

0.6–0.9 mg/kg i.v.;

CUROMID, ROCUNIUM 50 mg/5 ml, 100 mg/10 ml vials.


Mivacurium

0.07–0.15 mg/kg i.v.


Succinylcholine (Suxamethonium)

0.5–0.8 mg/kg i.v.;

MIDARINE, SCOLINE, MYORELEX, ENTUBATE 50 mg/ml in 2 ml amp.


Dantrolene

25–100 mg QID oral, 1 mg/kg i.v. repeated as required.


Carisoprodol

350 mg TDS–QID oral;

CARISOMA 350 mg tab;
SOMAFLAM 175 mg + ibuprofen 400 mg tab.


Chlorzoxazone

500 mg BD–TDS;

ULTRAZOX 250 mg + diclofenac 50 mg + paracetamol 325 mg tab;
MOBIZOX 500 mg + diclofenac 50 mg + paracetamol 500 mg tab;
PARAFON 250 mg + paracetamol 300 mg tab;
FLEXON-MR 250 mg + ibuprofen 400 mg + paracetamol 325 mg tab.


Chlormezanone

100–200 mg TDS–QID;

DOLOBAK 100 mg + paracetamol 450 mg tab.


Methocarbamol

400–800 mg TDS oral, 100–200 mg i.m./i.v.;
ROBINAX 0.5 g tab, 1 TDS 100 mg/ml inj. for i.v. or i.m. use.
ROBIFLAM 750 mg + ibuprofen 200 mg tab;
NEUROMOL-MR 400 mg + paracetamol 500 mg tab.


Baclofen

10 mg BD–25 mg TDS oral;

LIORESAL, LIOFEN 10, 25 mg tabs.


Thiocolchicoside

4 mg TDS-QID;

NUCOXIA-MR thiocolchicoside 4 mg + etoricoxib 60 mg tabs.


Tizanidine

2 mg TDS; max 24 mg/day;

SIRDALUD 2, 4, 6 mg tab;
TIZAN 2, 4 mg tab;
BRUFEN-MR, TIZAFEN 2 mg + ibuprofen 400 mg tab;
TIZANAC 2 mg + diclofenac 50 mg tab.,
PROXYVON-MR 2 mg + nimesulide 100 mg cap.


Peripherally Acting Muscle Relaxants

I. Neuromuscular blocking agents

A. Nondepolarizing (Competitive) blockers

  1. Long acting: d-Tubocurarine, Pancuronium, Doxacurium, Pipecuronium
  2. Intermediate acting: Vecuronium, Atracurium, Cisatracurium, Rocuronium, Rapacuronium
  3. Short acting: Mivacurium

B. Depolarizing blockers

Succinylcholine (SCh., Suxamethonium), Decamethonium (C-10)

II. Directly acting agents

Dantrolene sodium
Quinine

Centrally Acting Muscle Relaxants

  1. Mephenesin congeners: Mephenesin, Carisoprodol,
    Chlorzoxazone, Chlormezanone, Methocarbamol
  2. Benzodiazepines: Diazepam and others
  3. GABA derivative: Baclofen
  4. Central α2 agonist: Tizanidine