Aspirin
Antiinflammatory dose 3–5 g/day (75–100 mg/kg/day);
analgesic-antipyretic dose 0.3–0.6 g 6–8 hourly;
antiplatelet dose 75–150 mg/day.
ASPIRIN 350 mg tab,
COLSPRIN 100, 325 mg tabs,
ECOSPRIN 75, 150, 325 mg tabs,
DISPRIN 325 mg (with calcium carbonate 105 mg + citric acid 35 mg) tab,
LOPRIN 75, 162.5 mg tabs.
BIOSPIRIN Lysine acetylsalicylate 900 mg + glycine 100 mg/vial for dissolving in 5 ml water and i.v. injection.
Indomethacin
25–50 mg BD–QID. Those not tolerating the drug orally may be given nightly suppository.
IDICIN, INDOCAP 25 mg cap, 75 mg SR cap,
ARTICID 25, 50 mg cap,
INDOFLAM 25, 75 mg caps, 1% eye drop.
RECTICIN 50 mg suppository.
Ibuprofen
400–800 mg TDS;
BRUFEN, EMFLAM, IBUSYNTH 200, 400, 600 mg tab,
IBUGESIC also 100 mg/5 ml susp.
Naproxen
250 mg BD–TDS;
NAPROSYN, NAXID, ARTAGEN, XENOBID 250 mg tab,
NAPROSYN also 500 mg tab.
Ketoprofen
50–100 mg BD–TDS;
KETOFEN 50, 100 mg tab;
OSTOFEN 50 mg cap.
RHOFENID 100 mg tab, 200 mg SR tab; 100 mg/2 ml amp.
Flurbiprofen
50 mg BD–QID;
ARFLUR 50, 100 mg tab, 200 mg SR tab,
FLUROFEN 100 mg tab,
OCUFLUR 0.03% eye drops.
Mephenamic acid
250–500 mg TDS;
MEDOL 250, 500 mg cap;
MEFTAL 250, 500 mg tab, 100 mg/5 ml susp.
PONSTAN 125, 250, 500 mg tab, 50 mg/ml syrup.
Diclofenac
50 mg TDS, then BD oral, 75 mg deep i.m.;
VOVERAN, DICLONAC, MOVONAC 50 mg enteric coated tab, 100 mg S.R. tab, 25 mg/ml in 3 ml amp. for i.m. inj.
DICLOMAX 25, 50 mg tab, 75 mg/3 ml inj. Diclofenac potassium
VOLTAFLAM 25, 50 mg tab, ULTRA-K 50 mg tab;
VOVERAN 1% topical gel.
Aceclofenac
100 mg BD; ACECLO, DOLOKIND 100 mg tab, 200 mg SR tab.
Piroxicam
20 mg BD for two days followed by 20 mg OD;
DOLONEX, PIROX 10, 20 mg cap, 20 mg dispersible tab, 20 mg/ml inj in 1 and 2 ml amps;
PIRICAM 10, 20 mg cap.
Tenoxicam
20 mg OD; TOBITIL 20 mg tab.
Ketorolac
10–20 mg oral 6 hourly, 15–30 mg i.m./i.v. 6 hourly (max 90 mg/day);
KETOROL, ZOROVON, KETANOV, TOROLAC 10 mg tab, 30 mg in 1 ml amp.,
KETLUR, ACULAR 0.5% eye drops.
Nimesulide
100 mg BD;
NIMULID, NIMEGESIC, NIMODOL 100 mg tab, 50 mg/5 ml susp.
Meloxicam
7.5–15 mg OD;
MELFLAM, MEL–OD, MUVIK, M–CAM 7.5 mg, 15 mg tabs.
Nabumetone
500 mg OD;
NABUFLAM 500 mg tab.
Etodolac
200-400 mg BD-TDS;
ETOVA 200, 300, 400 mg tabs.
Celecoxib
100–200 mg BD;
CELACT, CELCOX, COLCIBRA, COBIX 100, 200 mg tabs.
Etoricoxib
60–120 mg OD;
TOROCOXIA, ETOXIB, ETOSHINE, NUCOXIA 60, 90, 120 mg tabs.
Parecoxib
40 mg oral/i.m./i.v. repeated after 6–12 hours (max. 80 mg/day);
PAROXIB 40 mg tab, REVALDO,
VALTO-P 40 mg/vial inj.
Paracetamol
325–650 mg (children 10–15 mg/kg) 3-5 times a day (max. 2600 mg/day); also 80–250 mg as suppository in infants and children; CROCIN 0.5 g tab, 125 mg/5 ml and 250 mg/5 ml syr, 100 mg/ml pediatric drops,
CROCIN PAIN RELIEF 650 mg with caffeine 50 mg tab;
METACIN, PARACIN 500 mg tab, 125 mg/5 ml syrup, 150 mg/ml ped. drops,
ULTRAGIN, PYRIGESIC, CALPOL 500 mg tab, 125 mg/5 ml syrup,
NEOMOL, FEVASTIN, FEBRINIL 300 mg/2 ml inj.
JUNIMOL-RDS 80, 170, 250 mg suppository, PARACETAMOL RECTAL SUPPOSITORY 80, 170 mg.
Metamizol
0.5–1.5 g oral/i.m./i.v.;
ANALGIN 0.5 g tab;
NOVALGIN, BARALGAN 0.5 g tab, 0.5 g/ml in 2 ml and 5 ml amps;
ULTRAGIN 0.5 g/ml inj in 2 ml amp and 30 ml vial.
Propiphenazone
300–600 mg TDS; marketed only in combi nation in several ‘over the counter’ preparations–in
SARIDON, ANAFEBRIN propiphenazone 150 mg + paracetamol 250 mg tab,
DART propiphenazone 150 mg + paracetamol 300 mg + caffeine 50 mg tab.
Nefopam
30–60 mg TDS oral, 20 mg i.m. 6 hourly; NEFOMAX 30 mg tab, 20 mg in 1 ml amp.
Topical NSAIDs
Diclofenac 1% gel
VOLINI GEL, RELAXYL GEL, DICLONAC GEL
Ibuprofen 10% gel
RIBUFEN GEL
Naproxen 10% gel
NAPROSYN GEL
Ketoprofen 2.5% gel
RHOFENID GEL
Flurbiprofen 5% gel
FROBEN GEL
Nimesulide 1% gel
NIMULID TRANS GEL, ZOLANDIN GEL, NIMEGESIC-T-GEL
Piroxicam 0.5% gel
DOLONEX GEL, MOVON GEL, PIROX GEL, MINICAM GEL
A. Nonselective COX inhibitors (conventional NSAIDs)
- Salicylates: Aspirin.
- Propionic acid derivatives: Ibuprofen, Naproxen,
Ketoprofen, Flurbiprofen. - Anthranilic acid derivative: Mephenamic acid.
- Aryl-acetic acid derivatives: Diclofenac, Aceclofenac.
- Oxicam derivatives: Piroxicam, Tenoxicam.
- Pyrrolo-pyrrole derivative: Ketorolac.
- Indole derivative: Indomethacin.
- Pyrazolone derivatives: Phenylbutazone, Oxyphenbutazone.
B. Preferential COX-2 inhibitors
Nimesulide, Meloxicam, Nabumetone, Etodolac.
C. Selective COX-2 inhibitors
Celecoxib, Etoricoxib, Parecoxib.
D. Analgesic-antipyretics with poor antiinflammatory
action
- Paraaminophenol derivative: Paracetamol (Aceta-
minophen). - Pyrazolone derivatives: Metamizol (Dipyrone),
Propiphenazone. - Benzoxazocine derivative: Nefopam